When a bone break is too severe to heal on its own, surgeons often rely on grafts or rigid metal implants — but both come with serious drawbacks. Now, researchers at ETH Zurich have created a ...

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Bones broken in a skiing accident usually heal on their own. But if the break is too severe or a bone tumor needs to be removed, surgeons insert an implant that enables the bone to grow back together.

Researchers found that mice lacking membrane ERα signaling in osteoblast lineage cells had significantly lower cortical bone mass, highlighting the pathway’s critical role in maintaining the strength ...