When it comes to identifying cancer-driving mutations, research has focused almost exclusively on understanding how mutations in the coding region of genes may alter a protein’s function to promote ...
In a recent study published in Nature, researchers in the United States aggregated and processed 76,156 human genomes to construct a genomic constraint map named "genomic non-coding constraint of ...
Researchers at Uppsala University have developed a new method to identify conserved noncoding mutations in the genome that may play a driving role in medulloblastoma brain tumors in children. The ...
Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people ...
Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.
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