In experimental settings, CB1 agonists like THC do alter sleep architecture, shifting NREM and REM balance and restructuring intermediate sleep stages.

This article was originally published on The Cannabis Community and appears here with permission. The discovery of the Endocannabinoid System (ECS) and its effects on the human body has landed itself ...

Plenty of recent research has shown compelling correlations between gut microbiome alterations and mood disorders such as depression. But exactly how bacteria in the gut could be influencing ...

The discovery of cannabis’s principal active ingredient is the stuff of scientific legend. In the early 1960s, a scientist in Israel named Raphael Mechoulam obtained some high-quality hashish from the ...

The endocannabinoid system is found throughout the brain and body and plays a key role in everything from memory and learning to sleep to social behavior. During prolonged aerobic exercise, the body's ...

In 1964, Israeli scientist Raphael Mechoulam isolated tetrahydrocannabinol, or THC, from a cannabis plant. Hundreds of chemicals exist in cannabis, not just the high-inducing THC and supposed-wellness ...

A Short History of Cannabis and Discovery of the ECS Medicinal plants have long been utilized for their beneficial effects, because many plants produce molecules that have chemical or functional ...

Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and decision-making, according to a study led by researchers at the Institute ...