Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...

Salt stress remains a critical challenge for plant growth, especially in crops like pea (Pisum sativum L.). This study explores the role of histone modifications in regulating pea's response to salt ...

Pharmacogenomic Strategies Provide a Rational Approach to the Treatment of Cisplatin-Resistant Patients With Advanced Cancer We used immunohistochemistry to assess histone 3 lysine 4 dimethylation ...

EpiciphAI公司正研发一款液体活检产品，通过检测无细胞染色质上的组蛋白标记，确定染色质片段的组织来源，并区分该组织中与疾病相关的状态。目前该公司仍处于种子前阶段，其技术的首个应用场景为难以进行活检的组织的癌症诊断与病情监测。

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

David Allis until his death in early 2023, have discovered surprising new details about the mechanics of this protein complex ...