New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...
A novel screening system developed at Kyoto University enables researchers to investigate sperm cell development and health at the molecular level. The new approach, published in Cell Genomics, ...
Human sperm have long been a subject of fascination—not just for their role in fertilization, but for their remarkable ability to navigate through some of the most viscous environments in the body.
A number of factors can play a decisive role in some couples' inability to conceive, which may lead them to turn to fertility treatments like IVF or IUI. But before couples get to that point, they ...
The day when human sperm and eggs can be grown in the laboratory has inched a step closer, with the discovery of a way to recreate a crucial developmental step in a dish 1. “Epigenetic reprogramming ...
The image shows centromeres (white) at the edge of the nucleus (blue) shortly before meiosis begins in a mouse germ cell (Huang et al., 2026). In our cells, our DNA carries chemical or ‘epigenetic’ ...
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Embryonic reproductive cells reveal striking genomic architecture before development
Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...
In our cells, our DNA carries chemical or 'epigenetic' marks that decide how genes will be used in different tissues. Yet in the group of specialised ...
Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...
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