A sum of 921 samples were collected from three independent data sets. We obtained pyroptosis-related genes from both the Molecular Signatures Database and relevant literature sources and used four ...

At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.

Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its ...

A study in mouse models and human tissue, carried out by researchers at the Barcelona Institute of Science and Technology Centre for Genomic Regulation (CRG), has found that the small nuceleolar RNA ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

The rapid emergence of antimicrobial resistance (AMR) poses a critical threat to global health, demanding innovative research strategies beyond conventional ...

Scientists have identified a new RNA molecule that may play a key role in improving survival in cancer patients.

Smaller noncoding RNA is being used in clinical practice and as knowledge grows of long noncoding RNA, use of it should follow, explained Laura Denby, PhD, Kidney Research UK Senior Fellow, senior ...

Crystal structure of the NHL domain of mouse TRIM71 complexed with a stem-loop structured Trincr1 RNA motif. Detailed interactions between key residues of TRIM71 and Trincr1 RNA are shown in an ...

A protein called LENG8 traps defective RNA molecules inside the cell nucleus before they can reach the cytoplasm and disrupt normal cellular function, according to a study published in Molecular Cell ...