Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical reactions ...

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a ...

Proteins are important molecules—but they aren’t the only molecules in a cell, and they don’t operate alone. In a new preprint, the team behind the protein structure prediction software RoseTTAFold ...