To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Researchers at the University of Illinois at Urbana-Champaign have shown for the first time that expensive aberration-corrected microscopes are no longer required to achieve record-breaking ...

Latest super-resolution microscopy methods now achieve an optical resolution in the range of a few nanometers. This corresponds to a resolution in the range of the size of cellular molecules. However, ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

(Nanowerk News) Cells, the fundamental units of life, contain a plethora of intricate structures, processes and mechanisms that uphold and perpetuate living systems. Many cellular core components, ...

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution. In contrast to traditional ...

This novel hybrid microscope allows for the simultaneous imaging of the full 3D orientation and position of molecules within cells. Researchers from the Marine Biological Laboratory (MA, USA) have ...