Scientists reprogrammed two widely used “chemically induced proximity” systems in a recent chemical science paper. CIP systems are very simple: when a small molecule is added, two engineered protein ...

Researchers develop synthetic markers that cross the blood-brain barrier, allowing for noninvasive monitoring of the living brain via blood tests.

Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, ...

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may ...

Gene therapy that can cross the blood–brain barrier represents a non-invasive way to map gene expression in the brains of ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...

Comprehensive epigenomic platform enables systematic and quantitative prediction of tumor gene expression from cell-free DNA Genes include key targets for next generation precision medicines, such as ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...