The Lancet

When to intubate in acute hypoxaemic respiratory failure? Options and opportunities for evidence-informed decision making in the intensive care unit

iDepartment of Medicine, Division of Respirology, University Health Network, Toronto, ON, Canada jInstitute of Health Policy, Management, and Evaluation at the University of Toronto, Toronto, ON, ...
BMJ

Severity of respiratory failure at admission and in-hospital mortality in patients with COVID-19: a prospective observational multicentre study

Objectives COVID-19 causes lung parenchymal and endothelial damage that lead to hypoxic acute respiratory failure (hARF). The influence of hARF severity on patients’ outcomes is still poorly ...
BMJ

Optimal plateau pressure for patients with acute respiratory distress syndrome: a protocol for a systematic review and meta-analysis with meta-regression

Introduction Lower tidal volume ventilation in patients with acute respiratory distress syndrome (ARDS) is a strategy to reduce the plateau pressure and driving pressure to limit ventilator-induced ...